UDC

612.135

Authors

Tveritina Elena Sergeevna
Postgraduate Student, Belgorod National Research University (Belgorod, Russia)

Abstract

Using Laser Doppler Flowmetry we established age-related differences in skin microvessel regulation in adolescents and young people during local heating. In thermoneutral environment, young girls, compared to older girls, had a higher neurogenic and myogenic vascular tone and a similar effect of the pulse wave and chest excursion on the blood flow. However, at local hyperthermia we observed blood flow modulation due to decreasing sympathetic effect on the vascular wall of arterioles, which causes an increase in shunting blood flow through arteriolovenular anastomoses. Older girls had changes mainly in the myogenic tone of the vascular wall with inclusion of passive factors of blood flow regulation, especially pronounced at the given end temperature.

Keywords

skin microvessels, thermoneutral conditions, local hyperthermia, blood flow regulation

References

1. Kozlov V.I. Sistema mikrotsirkulyatsii krovi: kliniko-morfologicheskie aspekty izucheniya [The System of Microcirculation: Clinical-Morphological Aspects of Studying]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya, 2006, vol. 5, no. 1 (17), pp. 84–101. 
2. Krasnikov G.V., Tankanag A.V., Konyaeva T.N. i dr. Otsenka izmeneniy v sisteme regulyatsii krovotoka v kozhe cheloveka pri lokal’nom nagreve [Assessment of the Changes in Regulatory Systems of Humаn’s Skin Blood Flow During Local Heating]. Rossiyskiy fiziologicheskiy zhurnal im. I.M. Sechenova, 2007, vol. 93, no. 4, pp. 394–401. 
3. Krupatkin A.I., Sidorov V.V. Lazernaya dopplerovskaya floumetriya mikrotsirkulyatsii krovi [Measurement of Microcirculation Using Laser Doppler Flowmetry]. Moscow, 2005. 123 p. 
4. Litvin F.B. Morfofunktsional’naya perestroyka sistemy mikrotsirkulyatsii u detey, podrostkov i yunoshey, prozhivayushchikh v mestakh s raznymi radioekologicheskimi usloviyami: dis. … dokt. biol. nauk [Morphofunctional Restructuring of the System of Microcirculation in Children, Adolescents and Young People Living in Areas with Various Radioecological Conditions: Dr. Biol. Sci. Diss.]. Moscow, 2006. 320 p. 
5. Fedorovich A.A. Funktsional’noe sostoyanie regulyatornykh mekhanizmov mikrotsirkulyatornogo krovotoka v norme i pri arterial’noy gipertonii po dannym lazernoy dopplerovskoy floumetrii [The Functional State of Regulatory Mechanisms of the Microcirculatory Blood Flow in Normal Conditions and in Arterial Hypertension According to Laser Doppler Flowmetry]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya, 2010, vol. 9, no. 1 (33), pp. 49–60. 
6. Tsekhmistrenko T.A., Stanishevskaya T.I. Individual’no-tipologicheskie osobennosti sostoyaniya mikrotsirkulyatsii krovi u devushek [Individual and Typological Features of Microcirculation in Girls]. Regionarnoe krovoobrashchenie i mikrotsirkulyatsiya, 2006, vol. 5, no. 1 (17), pp. 51–57. 
7. Bollinger A., Hoffmann U., Franzeck U.K. Evaluation of Flux Motion in Man by the Laser Doppler Technique. Blood Vessels, 1991, vol. 28. Suppl. 1, p. 21. 
8. Minson C.T., Berry L.T., Joyner M.J. Nitric Oxide and Neurally Mediated Regulation of Skin Blood Flow During Local Heating. J. Appl. Physiol., 2001, vol. 91, no. 4, pp. 1619–1626. 
9. Vallance P., Patton S., Bhagat K., et al. Direct Measurement of Nitric Oxide in Human Beings. Lancet, 1995, vol. 346, pp. 153–154. 
10. Wallin B.G. Neural Control of Human Skin Blood Flow. J. Auton. Nerv. System, 1990, vol. 30 (suppl), pp. 185–190.