UDC

[616.831-005:616.89-008.47]-053.2-073

Authors

Melkova Lyudmila Artemyevna
Institute of Medical and Biological Research, Northern (Arctic) Federal University named after M.V. Lomonosov (Arkhangelsk, Russia)
Fedotov Denis Mikhailovich
Institute of Medical and Biological Research, Northern (Arctic) Federal University named after M.V. Lomonosov (Arkhangelsk, Russia)
Bagretsova Tatyana Vladimirovna
Institute of Medical and Biological Research, Northern (Arctic) Federal University named after M.V. Lomonosov (Arkhangelsk, Russia)

Abstract

The paper studied cerebral blood flow using rheoencephalography in 153 boys aged 7–4 years with attention deficit hyperactivity disorder. We show that with age cerebral circulation undergoes reorganization. In the carotid and vertebrobasilar areas we observed a significant decrease in the majority of rheographic time and amplitude indicators. A significant reduction in the blood flow rate and intensity as well as improved venous outflow and circulation were observed in the carotid and vertebrobasilar areas. These changes in the circulation rate indicate increased vascular tone of distributing vessels (large and medium-sized) and, consequently, their improved capacity, which is an important factor for the mechanisms regulating blood supply to the brain. The increasing blood supply rate in the left hemisphere and decreasing one – in the right hemisphere is considered to be a compensatory response due to the functional dominance of the left hemisphere in the majority of people. The obtained results support those of previous studies and suggest a physiological age-related economization of cerebral circulation. We must point out, however, that functional deviations in microvasculature (increased tone of arterioles, precapillaries, postcapillaries and venules compared to the age norm) are preserved. These changes are consistent with the generally accepted views on a child’s functional development and are caused by the microvasculature adapting to the metabolic needs of the brain in children with ADHD.

Keywords

primary and middle school age, cerebral hemodynamics, attention deficit hyperactivity disorder

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