UDC

612.135

Authors

Baboshina Natalya Vladimirovna
Postgraduate Student, Yaroslavl State Pedagogical University named after K.D. Ushinsky
108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation;
e-mail: i.tikhomirova@yspu.org
Tikhomirova Irina Aleksandrovna
Yaroslavl State Pedagogical University named after K.D. Ushinsky
108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation;
e-mail: pankrateva@bk.ru
Malysheva Yuliya Viktorovna
Postgraduate Student, Yaroslavl State Pedagogical University named after K.D. Ushinsky
108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation;
e-mail: yulichkinka@mail.ru

Abstract

The study of the microcirculation system in ontogenesis is an important area of developmental physiology. It looks at the formation and functioning of human microvasculature at different age stages. Peripheral blood flow takes place in the vessels of individual organs and tissues and provides adequate blood supply to them adjusting to the constantly changing metabolic activity. We used Laser Doppler Flowmetry (LDF) together with the wavelet analysis of the amplitude-frequency spectrum of microcirculatory fluctuations to evaluate skin microcirculation and its regulatory mechanisms in children of both sexes twice: in 2013 and 2015 (upon their reaching the age of 8 and 10 years). During the age period from 8 to 10 years, tissue perfusion increased by 62.1 % and 68.2 % (p < 0.001) in both girls and boys, respectively. The rising values of microcirculation within this age period are associated with high intensity of metabolic processes due to the changes in the mechanisms of microcirculatory regulation during the transition to adolescence. The values of maximum oscillation amplitudes in all active factor ranges of microcirculatory regulation increased over two years both in boys and in girls. No significant differences were observed between microcirculation parameters of girls and boys aged 10 years. The values of normalized amplitudes of myogenic and respiratory rhythms in boys were credibly higher, while those of cardiac oscillations lower than in girls (р < 0.05). The analysis of the obtained data indicates both age-related (between 8 and 10 years) differences in microcirculation and emerging during this period sex-related differences in the functioning of regulatory mechanisms of microcirculation.

Keywords

microcirculation in primary school children, Laser Doppler Flowmetry, regulatory mechanisms of microcirculation, age-related changes

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