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Relationship Between Vitamin D Level and Functional State of Patients with Osteoarthritis Aged 60–80 Years Living in Murmansk. P. 86-94

Версия для печати

Section: Medical and biological sciences

UDC

612.66:616.72-002

DOI

10.37482/2687-1491-Z132

Authors

Maksim D. Kashpanov* ORCID: https://orcid.org/0000-0002-5826-9868
Vladimir V. Popov** ORCID: https://orcid.org/0000-0003-2281-0576
Irina A. Novikova** ORCID: https://orcid.org/0000-0002-3437-5877

*City Outpatient Clinic No. 2 (Murmansk, Russian Federation)
**Northern State Medical University (Arkhangelsk, Russian Federation)

Corresponding author: Maksim Kashpanov, address: prosp. Kol’skiy 149A, Murmansk, 183052, Russian Federation; e-mail: kashpanovm@mail.ru

Abstract

The purpose of this paper was to identify the relationship between the level of vitamin D and the functional state parameters in older patients with osteoarthritis. Materials and Methods. The study involved 100 subjects (85 women and 15 men) aged between 60 and 80 years (mean age 69.03 ± 2.34 years) receiving treatment at outpatient facilities in Murmansk. The following research methods were used: questionnaire, clinical examination, X-Ray, and serum vitamin D testing. The radiographic stage of osteoarthritis and the degree of joint dysfunction were determined. We used the Age Is Not a Barrier Questionnaire, Hospital Anxiety and Depression Scale, Pain Visual Analogue Scale, Mini Nutrition Assessment Questionnaire, and SF-36 Quality of Life Questionnaire. Results. We found that 1/3 of the patients with osteoarthritis aged 60–80 years had vitamin D deficiency, while over 1/2 of them had vitamin D insufficiency. Patients with vitamin D deficiency were more likely to show signs of a risk of malnutrition than those with vitamin D insufficiency, as well as a more pronounced pain syndrome, higher radiographic stages of osteoarthritis and degrees of joint dysfunction, as well as higher rates of anxiety and depression, and lower quality of life. Quality of life was lower in patients with higher levels of anxiety and depression, as well as with a more pronounced radiographic stage of osteoarthritis. The results of this study indicate advisability of including vitamin D in the combination therapy of osteoarthritis in patients aged 60–80 years.

Keywords

vitamin D level, osteoarthritis, psychofunctional state, older patients, radiographic stage of osteoarthritis, degree of joint dysfunction, quality of life scores
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References

  1. Kolasinski S.L., Neogi T., Hochberg M.C., Oatis C., Guyatt G., Block J., Callahan L., Copenhaver C., Dodge C., Felson D., Gellar K., Harvey W.F., Hawker G., Herzig E., Kwoh C.K., Nelson A.E., Samuels J., Scanzello C., White D., Wise B., Altman R.D., DiRenzo D., Fontanarosa J., Giradi G., Ishimori M., Misra D., Shah A.A., Shmagel A.K., Thoma L.M., Turgunbaev M., Turner A.S., Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Rheumatol., 2020, vol. 72, no. 2, pp. 220–233. DOI: 10.1002/art.41142
  2. Musumeci G., Aiello F.C., Szychlinska M.A., Di Rosa M., Castrogiovanni P., Mobasheri A. Osteoarthritis in the XXIst Century: Risk Factors and Behaviours That Influence Disease Onset and Progression. Int. J. Mol. Sci., 2015, vol. 16, no. 3, pp. 6093–6112. DOI: 10.3390/ijms16036093
  3. Galushko E.A., Nasonov E.L. Prevalence of Rheumatic Diseases in Russia. Al’manakh klinicheskoy meditsiny, 2018, vol. 46, no. 1, pp. 32–39 (in Russ.). DOI: 10.18786/2072-0505-2018-46-1-32-39
  4. Nasonov E.L., Gordeev A.V., Galushko E.A. Revmaticheskie zabolevaniya i mul’timorbidnost’ [Rheumatic Diseases and Multimorbidity]. Terapevticheskiy arkhiv, 2015, vol. 87, no. 5, pp. 4–9. DOI: 10.17116/terarkh20158754-9
  5. Karonova T.L., Grineva E.N., Nikitina I.L., Tsvetkova E.V., Todieva A.M., Belyaeva O.D., Mikheeva E.P., Globa P.Yu., Andreeva A.T., Beletskaya I.S., Omel’chuk N.V., Fulonova L.S., Shlyakhto E.V. Uroven’ obespechennosti vitaminom D zhiteley severo-zapadnogo regiona RF (g. Sankt-Peterburg i g. Petrozavodsk) [The Prevalence of Vitamin D Deficiency in the Northwestern Region of the Russian Federation Among the Residents of St. Petersburg and Petrozavodsk]. Osteoporoz i osteopatii, 2013, no. 3, pp. 3–7.
  6. Kodentsova V.M., Mendel’ O.I., Khotimchenko S.A., Baturin A.K., Nikityuk D.B., Tutel’yan V.A. Fiziologicheskaya potrebnost’ i effektivnye dozy vitamina D dlya korrektsii ego defitsita. Sovremennoe sostoyanie problemy [Physiological Needs and Effective Doses of Vitamin D for Deficiency Correction. Current State of the Problem]. Voprosy pitaniya, 2017, vol. 86, no. 2, pp. 47–62.
  7. Malyavskaya S.I., Kostrova G.N., Lebedev A.V., Golysheva E.V. Provision of Different Age-Group Populations of Arkhangelsk City with Vitamin D. Ekologiya cheloveka, 2016, no. 12, pp. 37–42 (in Russ.). DOI: 10.33396/1728-0869-2016-12-37-42
  8. Murmanskaya oblast’ v tsifrakh [Murmansk Region in Figures]. Murmansk, 2021. 127 p.
  9. Tkacheva O.N., Runikhina N.K., Ostapenko V.S., Sharashkina N.V., Mkhitaryan E.A., Onuchina Yu.S., Lysenkov S.N. Validatsiya oprosnika dlya skrininga sindroma starcheskoy astenii v ambulatornoy praktike [Validation of the Questionnaire for Screening Frailty]. Uspekhi gerontologii, 2017, vol. 30, no. 2, pp. 236–242.
  10. Zigmond A.S., Snaith R.P. The Hospital Anxiety and Depression Scale. Acta Psychiatr. Scand., 1983, vol. 67, no. 6, pp. 361–370. DOI: 10.1111/j.1600-0447.1983.tb09716.x
  11. Breivik H., Borchgrevink P.C., Allen S.M., Rosseland L.A., Romundstad L., Hals E.K., Kvarstein G., Stubhaug A. Assessment of Pain. Br. J. Anaesth., 2008, vol. 101, no. 1, pp. 17–24. DOI: 10.1093/bja/aen103
  12. Ware J.E., Kosinski M., Keller S.D. SF-36 Physical and Mental Health Summary Scales: A Userʼs Manual. Boston, 1994.
  13. Guigoz Y., Vellas B. The Mini Nutritional Assessment (MNA) for Grading the Nutritional State of Elderly Patients: Presentation of the MNA, History and Validation. Nestle Nutr. Workshop Ser. Clin. Perform. Programme, 1999, vol. 1, pp. 3–11. DOI: 10.1159/000062967



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